Metformin a medicine for diabetes

Metformin For Diabetes : Uses And Side Effects

(Last Updated On: January 24, 2018)

What is Metformin ?

Metformin is an oral diabetes drug that helps control blood sugar levels.

Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Metformin is sometimes used together with insulin or different medications, however, it’s not for treating type 1 diabetes. Visit Link For Type 2 Diabetes Symptoms.

It Available Under the brand names of Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet.

Metformin Uses

Metformin is used for treating type 2 diabetes in adults and kids. it’s going to be used alone or together with other diabetic medications.

Metformin also has been used to stop the development of diabetes in people in danger for diabetes, treatment of polycystic ovaries, and weight gain due to medications used for treating psychoses.

Metformin side effects

The most common side effects of metformin are

nausea,  

vomiting,

gas,

bloating,

diarrhea and

loss of appetite.

These symptoms occur in one out of every 3 patients. These side effects could also be severe enough to cause therapy to be discontinued in one out of every 20 patients. These side effects are associated with the dose of the medication and should decrease if the dose is reduced.Visit Link For Skin Cancer symptoms.

Metformin might also cause:

weakness,

respiratory tract infections,

low levels of vitamin B-12,

low blood glucose,

heartburn, and

chills.

A serious however rare side effect of metformin is lactic acidosis Visit Link To Know About Plavix Drug For Heart Attack. lactic acidosis occurs in one out of every 30,000 patients and is fatal in 500th of cases.

The symptoms of lactic acidosis are :

weakness,

trouble breathing,

abnormal heartbeats,

uncommon muscle pain,

stomach discomfort,

light-headedness, and

feeling cold.

Patients in danger of lactic acidosis include those with reduced function of the :

kidneys or liver,

congestive heart failure,

severe acute illnesses, and

dehydration.

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Precaution

if you’re allergic to it, You should not use metformin, or if you have:

severe kidney disease; or

metabolic or diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that’s injected into your veins, you’ll ought to temporarily stop taking metformin.Visit link to know about symptoms of mesothelioma.

To make certain this medication is safe for you, tell your doctor if you have ever had:

kidney disease (your kidney function may need to be checked before you take this medicine);

high ketone levels in your blood or urine;

heart disease, congestive heart failure;

liver disease; or

if you also use insulin or other oral diabetes medications.

Some people using metformin develop a serious disease referred to as lactic acidosis. this could be more probably if you have liver or kidney disease, congestive heart failure, surgery, a heart attack or stroke, a severe infection, if you’re 65 or older, if you’re dehydrated, or if you drink plenty of alcohol. talk with your doctor about your risk.

Follow your doctor’s instructions about using this medication if you’re pregnant. blood sugar control is very necessary during pregnancy, and your dose needs could also be different throughout every trimester of pregnancy. Tell your doctor if you become pregnant while taking metformin.Visit Link To know about best mesothelioma doctor near you.

It is not known whether metformin passes into breast milk or if it could damage a nursing baby. you should not breast-feed while using this medication.

Metformin should not be given to a child younger than 10 years old. Some forms of metformin are not approved for use by anyone younger than 18 years old.

Metformin Dosage

Metformin (immediate release) usually is started at a dose of 500 mg two times a day or 850 mg once daily for treating type 2 diabetes in adults. The dose is gradually increased by 500 mg weekly or 850 mg every two weeks as tolerated and based on the response of the levels of glucose in the blood. the maximum daily dose is 2550 mg given in 3 divided doses.

If extended tablets are used, the beginning dose is 500 mg or 1000 mg daily with the evening meal. The dose is often increased by 500 mg weekly up to a maximum dose of 2000 mg apart from Fortamet (2500 mg of Fortamet, once daily or in 2 divided doses). Fortamet and Glumetza have updated release formulations of metformin where Glumetza tablets (500 -1000mg formulations are provided one daily (either 1000 to 2000mg). It should be taken with meals.

For pediatric patients 10-16 years of age, the beginning dose is 500 mg twice a day. The dose can be increased by 500 mg weekly up to a maximum dose of 2000 mg in divided doses.

Children older than 17 years of age could take 500 mg of extended-release tablets regular up to a maximum dose of 2000 mg daily. Extended-release tablets are not approved for children younger than 17 years of age.

Metformin-containing drugs may be safely used in patients with mild to moderate renal impairment. renal function should be assessed before beginning treatment and at least yearly.

Metformin shouldn’t be used by patients with an estimated glomerular filtration rate (eGFR) below 30 mL/minute/1.73 m2 and starting metformin in patients with an eGFR between 30-45 mL/minute/1.73 m2 isn’t suggested.

This Drug should be discontinued at the time of or before administering iodinated contrast in patients with an eGFR between 30 and 60 mL/minute/1.73 m2; in patients with a past of liver disease, alcoholism, or heart failure; or in patients who are administered intra-arterial iodinated contrast. kidney function should be estimated 48 hours once receiving contrast and metformin is also restarted if kidney function is stable.

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When You Missed Dose

Take the missed dose as soon as you remember (be sure to take the drugs with food). Skip the missed dose if it is nearly time for your next programmed dose. don’t take extra medicine to create up the missed dose.

When You Overdoes

Seek emergency medical attention or call the Poison helpline at 1-800-222-1222. an overdose of metformin might cause lactic acidosis, which can be fatal.

Avoid These Things

Avoid drinking alcohol. It lowers blood sugar and should increase your risk of lactic acidosis while taking metformin.

Affect Of Different Medicine On Metformin

Sometimes it is not safe to use certain medications at the same time. Some medication will affect your blood levels of other medication you are taking, which can increase side effects or make the medications less effective.

Other medication might interact with metformin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all of your current medicines and any medicine you begin or stop using.

Preparations

Tablets: 500, 850, and 1000 mg

Tablets (extended release): 500, 750, and 1000 mg.

Solution: 100 mg/ ml

This Drug should be stored at room temperature between 20 C to 25 C (68 F to 77 F).

Sources :

Wikipedia

American Diabetes Association®

 

 

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