1 )What is Plavix and How Does It Works ?
Plavix is a prescription medicine that stops platelets from clumping together and forming blood clots. It helps blood flow more easily and reduces the chance of a future stroke or heart attack.
Plavix works by keeping platelets apart and stopping them sticking together and forming clots. It helps reduce the chance of a future stroke or heart failure in this way.
The drug achieves this result because it is a platelet inhibitor. It reduces the quantity of platelets in the blood. This limits the ability of the blood to clot.
Plavix is used to prevent blood clots in patients who have recently had a heart failure or stroke and people with the cerebrovascular disease.
The cerebrovascular disease affects the blood vessels that provide blood and oxygen to the brain. Patients face a high risk of a stroke following a diagnosis.
2) What is Plavix Used to Treat ?
Heart Disease :
Plavix will help patients with coronary heart disease (CHD), also called coronary artery disease (CAD). In CHD, one or more arteries do not supply enough blood to the heart.
This sometimes happens because the arteries have hardened. The hardening of arteries is termed atherosclerosis.
CHD is a major cause of illness and death around the world. It starts when plaque, a substance made from hard cholesterol, collects within a coronary artery.
As the plaque builds up, it will cause the formation of little blood clots. These clots will stop blood reaching the heart muscle.
Chest pain, also called angina pectoris, is a common symptom. CHD will cause a heart attack or sudden death.
Peripheral Vascular Disease :
Peripheral vascular disease (PVD) refers to diseases of the blood vessels that are not directly connected to the heart. The peripheral blood vessels narrow, and blood flow is restricted. It mostly happens in the legs, and sometimes in the arms.
The patient could 1st notice tired and aching leg muscles, particularly when walking.
Symptoms could resolve during rest.
As the disease gets worse, symptoms can seem even during light exertion. Eventually, they will be present all the time. when the disease is severe, the leg and foot could feel cold when touched, and therefore the patient can feel constant numbness. Gangrene will develop in some cases.
Plavix can be important in limiting the harmful effects of these conditions.
3) What Form Does Plavix Come ?
Plavix 75 mg
Each circular, pink, biconvex, film-coated pill, marked with “75” on one face and “1171” on the opposite, includes clopidogrel bisulfate 97.9 mg that offers 75 mg of clopidogrel base.
nonmedicinal ingredients: hydrogenated castor oil, low substituted hydroxypropyl cellulose, cellulose, mannitol, microcrystalline and polyethylene glycol 6000; coating: carnauba wax, hypromellose, lactose, red iron oxide, titanium dioxide, and triacetin.
Plavix 300 mg
Each oblong, pink, film-coated pill, engraved with “300” on one side and “1332” on the opposite, contains clopidogrel bisulfate 391.5 mg that provides 300 mg of clopidogrel base.
nonmedicinal ingredients: low substituted hydroxypropyl cellulose, mannitol, microcrystalline cellulose, hydrogenated castor oil and polyethylene glycol 6000; coating: carnauba wax, hypromellose, lactose, red iron oxide, titanium dioxide, and triacetin.
4) How to use Plavix (Plavix Dosage)
Read the Medicine Guide provided by your pharmacologist before you begin using clopidogrel and every time you get a refill. If you have any queries, ask your doctor or pharmacist.
Take this medication orally with or without food as directed by your doctor, usually once daily. Take this medication regularly to get the most benefit from it. to help you remember, take it at a similar time every day.
The dose and length of treatment are based on your medical condition and response to treatment. If you’re taking this medication to stop clots after a stent implant or other procedure, take this medication with aspirin for several months to years after the procedure (depending on the method/type of stent) as directed by your doctor.
Consult your doctor for more details and about the dangers of stopping early. it’s necessary to continue taking this medication even if you’re feeling well. don’t stop taking this medication without consulting your doctor.
Avoid consuming grapefruit or drinking grapefruit juice while using this medication except your doctor or pharmacist says you will do so securely.
Grapefruit will increase the possibility of side effects with this medicine. ask your doctor or pharmacist for more details.
Take medical help immediately if you have any signs that this medicine isn’t working, like signs of a new heart attack or stroke (such as chest/jaw/left arm pain, shortness of breath, uncommon sweating, weakness on one side of the body, slurred speech, sudden vision changes, confusion).
5) Plavix Overdose
If somebody has overdosed and has dangerous symptoms like passing out or struggle to breathe, call 911. Otherwise, call a poison control center immediately.
United States residents will call their native poison control center at 1-800-222-1222. Canada residents will call a provincial poison control center.
Do not share this medication with others.
Lab tests (such as complete blood count) is also performed systematically to watch your progress or check for Adverse effects of medicine. Consult your doctor for more details.
Plavix missed dose
If you miss a dose, take it as quickly as you memorize. If it is near to the time of the next dose, skip the missed dose. Take your next dose at the routine time. do not increase the dose to catch up.
Store at room temperature away from light and wetness. don’t store in the bathroom. Keep all medications away from kids and pets.
Do not flush medications down the bathroom or pour them into a drain unless instructed to do so. Properly discard this product when it’s expired or no longer required. Consult your pharmacist or native waste disposal company.
6) Plavix Side Effect
Plavix has some unintentional side effects that warrant a degree of caution when taking the drug.
Taking plavix will commonly result in bleeding and itchy skin.
More serious side effects also can occur, including:
♦ unexplained or persistent bleeding
♦ blood in the urine that changes the color pink, brown, or red
♦ red or tar-black stools
♦ unexplained, growing bruises
♦ coughing up or vomiting blood
Thrombocytopenic purpura (TTP) can also occur as a result of taking plavix. this can be a condition that causes blood clots to seem anywhere in the body, resulting in severe symptoms. These include:
purple colored spots in the mouth or bleeding below the skin
♦ pale skin
♦ high body temperature
♦ tachycardia, or quick heart rate
♦ difficulty breathing
♦ problem understanding speech and language
♦ low urine output
♦ abdominal pain
♦ vision loss
If you notice any of these symptoms, contact a doctor instantly.
7) Plavix Precautions
Plavix needs some precautions before use, relating to storage, travel, and monitoring requirements. These include:
♦ Take the pill whole: don’t crush or cut the pill.
♦ call the pharmacy before visiting: If Plavix has been prescribed, not every pharmacist stocks the branded version as opposed to the generic product.
♦ Store correctly: Clopidogrel needs storage in a dry place at room temperature, about 77°F or 25°C. don’t leave this medication in the car.
Also Read : Atorvastatin medicine to prevent heart attack
♦ Carry the prescription with you when traveling by air: this may permit airport security to spot the drugs as necessary for health reasons.
♦ Avoid elective dental work or operations while taking Plavix: Plavix impacts bleeding time and platelet production for 7 to 10 days. Avoid surgery that is not medically essential throughout this time to avoid the chance of severe bleeding.
♦ Tell your doctor or pharmacist if you are allergic to it, or to related antiplatelet medicine (thienopyridines like prasugrel); or if you have the other allergies before taking medicine.
♦ Tell your doctor or dentist about all the product you use (including prescription drugs, nonprescription medicine, and herbal products) before having surgery, Your doctor could instruct you to prevent clopidogrel for a minimum of 5 days before surgery. don’t stop taking clopidogrel without talking with your heart doctor (cardiologist) first.
♦ Avoid Daily use of Alcohol : ask your doctor how much alcohol you could consume safely.
♦ During pregnancy, this medication ought to be used only clearly required. Discuss the risks and advantages with your doctor.
♦ It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.